Difference between 'db.collection' vs 'new mongo.Collection'

Are there any differences (besides method 1 being async) between method 1 and 2 to obtain a reference to a mongodb collection shown below?

var mongo = require('mongodb');
var db= new mongo.Db('blog', new mongo.Server(host, port, {auto_reconnect: true}, {}));
db.open(function(){
    //Method 1
    db.collection('articles', function(err, result){
        var collection1 = result;
    });

    //Method 2
    var collection2 = new mongo.Collection(db, 'articles');
});