Nodejs - Multiple File or Single File Database?

The question explains itself. But which do you think is better? Using a multiple file database or a single file database?

The data has to be accessed by multiple clients, which means that it has to be robust in reading data. Which means that a single file database will be much faster, but if something fails, my data can become corrupted, and I don't want that. If I'll go for multiple file database, I am worried about the file overhead. Which do you think is better? :)

use a single file database for nodejs with nginx