Nodejs server communicate with two network interface cards

Is it possible with a nodejs server to have it receive a message on one network interface and then output an HTTP request on a different network interface?

The scenario: I have a device on a local network and I want the server to be able to receive data from that and format it into a request to update a third party web app. I have confirmed that I am receiving the local message correctly, and I have confirmed that the format of the HTTP request should work using fiddler, but somewhere between the two parts I am having an issue. I get a "socket hang up" error at the moment.

Thanks in advance

Edit: Below is my server code. I have specified IP addresses for the incoming and outgoing messages, but I still get a socket hang up error. Can anyone spot anything else which could be causing this issue?
I am wondering if I need to do something differently for a secure connection? (it is a https URL)

var url = require("url");
var http = require('http');


http.createServer(function (request,response) {
    var theUrl = url.parse(request.url);
    console.log(theUrl);
    var timeline = {   // Data to be sent to external web service
        channel: "#test",
        username: "Slash",
        icon_emoji: ":smirk_cat:",
        text: "Timeline Started: " + theUrl.path
    };
    var data = JSON.stringify(timeline)

    var options = {
        host: "example.com",
        path: "/path/to/web/service",
        localAddress: '172.20.1.53', // IP address of outgoing NIC
        method: 'POST',
        port: "443",
        headers: {
            'Content-Type': 'application/json',
            'Content-Length': Buffer.byteLength(data),
        }
    };

    var req = http.request(options, function(res){
        res.on('data', function(resp) {
            console.log(resp)
        });
    });
    req.on('error', function(err) {
        console.log("ERROR: " + err.message);
    });
    req.write(data);
    console.log(req);
    req.end();
}).listen(801, '172.30.2.92'); // IP address of incoming NIC